Arginine is one of the essential provisional essential amino acid that helps the body to produce necessary proteins that are important for the various functions that the body requires. Its considered provisionally essential because its very easy for people that are deemed healthy to get it from daily diet by infusing into the body via the kidneys.
Nearly all arginine in the body can be used to process ammonia in the less toxic urea, also to synthesize creatine and ornithine. A small part is subsequently employed as a precursor to nitric oxide (NO), a compound which dilates blood vessels, lowers blood pressure, and helps maintain a healthy cardiovascular system [R].
Over the years, L-arginine has been found to be very useful when used with some over-the-counter prescription medication to solve many health related problems. For instance, L-arginine is commonly used alongside aspirin for migraine headaches, can be taken with chemotherapy drugs for treating breast cancers and when used with additional amino acids can help treat people infected with AIDS for weight loss including using it with fish oil and other supplements for reducing infections, improving wound healing, and shortening recovery time after surgery.
Other Uses Of L-Arginine
L-arginine can also be used for recurrent pain in the legs because of blocked arteries, diminished mental ability in the older (senile dementia), erectile dysfunction (ED), altitude illness, nitrate tolerance, diabetes, diabetic nerve pain, kidney toxicity from cyclosporine, kidney disease, tuberculosis, critical illness, head and neck cancer, obesity, ovary disease (polycystic ovary syndrome), stress ulcers, respiratory infections, sickle cell disease, anxiety, and male infertility.
Best Source Of L-Arginine
L-arginine can be found in red meat, poultry, fish, and dairy products. In addition, it can be produced in a lab and used as medicine.
Though L-arginine is deemed safe in moderate doses, a lot of L-arginine can have serious side effects, such as death. It’s very important to realize the way the supplement might interact with the body and also with additional medications before carrying it.
Benefits of L-arginine
L-arginine has a range of possible benefits which vary from heart health and chest pain to assisting build muscles, repair wounds, and improve male fertility.
L-Arginine Helps Reduce Blood Pressure And Improve Blood Flow
Nitric Oxide is produced by cells from the body to lower blood pressure and also to increase blood flow by expanding and relaxing the blood vessels to stop blood clots. It is also very useful in preventing Nitric Oxide from breaking down and also reduces the risk of hypertension and stroke.
L-Arginine Supplementation Helps Reduce Risk of Heart Disease
A controlled study performed in humans found that L-Arginine levels were always lower in coronary heart disease (CHD) patients than they had been in healthy controls.
L-Arginine Supplementation Helps Reduce Risk of Type 2 Diabetes
The same controlled human research found that Type 2 Diabetes patients always had lower levels of L-Arginine than healthy controls. L-Arginine supplementation could be helpful in restoring plasma imbalances in those patients.
L-Arginine Works as an Antioxidant in Type 2 Diabetic Patients
Type 2 Diabetes causes oxidative stress and damage in patients. Controlled human studies have revealed that L-Arginine supplementation might help reduce the effect in Diabetic (type 2) patients.
The research found that L-Arginine indirectly activated SOD (a free radical scavenger protein) to reduce oxidative damage.
Using L-Arginine Can Helps Increase Immune Reaction
Various studies have demonstrated that increased amounts of Nitric Oxide will increase immune reaction in the body. Nitric Oxide can stimulate the immune system to act on and destroy pathogens [R].
As mentioned, L-Arginine was proven to increase levels of Nitric Oxide.
Using L-Arginine Supplementation Can Increases Stamina
Various studies have revealed that L-arginine can reduce the total amount of oxygen required by muscles during exercise. This increases the total amount of time that a muscle may be exercised until it’s exhausted.
Using L-Arginine Can Improves Wound Healing
Recent study carried out on mice discovered that L-arginine supplementation can improves wound healing by increasing Nitric Oxide. Nitric Oxide may also increase collagen production, which assists in the wound healing process.
Using L-Arginine Can Aid In Improving Cognitive Memory through Aging
Study demonstrated that maintaining Nitric Oxide levels appears to be very important in memory functioning. It’s a known fact that due to aging, there is significant reduction in the level of arginine in some parts of the brain that is related to memory which can lead to decreasing in Nitric Oxide level and diminished memory function.
Supplementation could prevent L-Arginine and Nitric Oxide levels from falling.
Using L-Arginine Can Helps Increase Fertility
In women, low fertility is most frequently brought on by a poor ovarian response to hormones [R]. Low fertility is mostly caused by poor ovarian response to hormones in women and a research discovered that L-arginine when taken together with some other supplements can actually increase the pregnancy rates by increasing ovarian reactions to hormones. Also low sperm count or low sperm motility in men can be be caused when there is lack of Arginine.
A research done on men discovered that supplementation with L-Arginine contributes to increased production of Nitric Oxide, which protects sperm from oxidative damage. This protection was found to increase sperm motility and sperm count.
Using L-Arginine Supplementation Fights Aging
A study in humans found that Nitric Oxide levels decrease with age. This reduction may result in serious conditions like Heart Disease and Diabetes.
L-Arginine supplementation could be helpful in maintaining normal Nitric Oxide levels so as to counterbalance the aging process.
Using L-Arginine Supplementation Reduce Chest pain (angina) Symptoms.
Taking L-arginine seems to reduce chest pain symptoms and improve exercise tolerance and quality of life in people with angina. But, L-arginine doesn’t appear to help expand the blood vessels which are narrowed in angina.
Using L-Arginine Supplementation Can Help Erectile dysfunction (ED).
Taking 5 g of oral L-arginine daily appears to improve sexual function in men with ED. Taking lower doses may not be effective. But, there’s some historical evidence that carrying L-arginine with maritime pine bark extract and other components, may improve the effectiveness of low-dose L-arginine for ED.
Inflammation and tissue death in the digestive tract from premature infants (necrotizing enterocolitis).
Adding L-arginine to formulation appears to prevent inflammation of the digestive tract from premature infants. A total of 5 premature infants will need to obtain arginine to prevent 1 case of digestive tract inflammation.
Side Effects of L-Arginine Supplementation
Too much L-Arginine can boost an autoimmune response
Nitric Oxide can respond with Hydrogen Peroxide from the body to produce free radicals. These free radicals may lead to oxidative damage and cell death. As a result of this, much Nitric Oxide in the body may result in an increased chance of an autoimmune reaction.
High levels of L-Arginine could promote Nitric Oxide buildup, causing this reaction to occur.
L-Arginine Can Serve as a Laxative When Taken On An Empty Stomach
There are reports of L-Arginine causing nausea if it’s taken on an empty stomach. This is exceedingly rare but it’s almost always best to take the supplement with meals as a precaution.
Other benign and common side effects include:
- Abdominal pain
- airway inflammation
- low blood pressure
- blood abnormalities
- worsening of asthma
But, L-arginine may lead to some severe complications that have to be considered. L-arginine has some potentially severe dangers for specific groups of individuals.
- Serious illness or death in children and infants
- Difficulty controlling blood pressure during surgery
- Worsening of herpes
- Increased probability of death following a heart attack
- Negative interaction with certain medications, such as Viagra and blood pressure medications
Even though there are dangers connected with L-arginine, most research suggests it’s safe for people to take in small doses. The U.S. Food and Drug Administration (FDA) don’t track the safety or effectiveness of supplements, therefore it’s necessary to select a respectable brand.
L-Arginine: Dosage, how long does it take for l arginine to work:
L-Arginine is produced in the body but happens at quite low levels. Because of this, L-Arginine supplementation may occasionally be helpful as one ages. The receptor Nitric Oxide Synthase Employs L-Arginine to create Nitric Oxide and L-Citrulline.
The average dietary intake of L Arginine is 5.4 g every day.
L-Arginine are available in red meat, fish, dairy, nuts, and poultry.
The molecule may also be obtained as a nutritional supplement in 500mg capsules.
Studies have revealed that there are not many negative side effects of carrying L-Arginine at daily doses of 20 g or under.
As stated previously, it could be recommended to take L-Arginine with meals to prevent the negative effects. Since L-Arginine has quite low absorption levels in the liver, intravenous supplementation of arginine might be advocated in extreme instances.
Best Nitric Oxide Supplements
Thus far just one nitric oxide supplementation has been mentioned: L-arginine. And it is said to be a popular supplement in the market, but that is not because it is the best. In reality, research shows it is quite unreliable, working well in some individuals and not in others.
This can help explain why one person will swear by one nitric oxide supplement or some other while somebody else will encounter no effects or benefits at all.
Fortunately, there are other options, and also the best is just another amino acid called